cardinalkarp wrote: ↑July 29 21, 9:06 am
My argument in not getting the vaccine has never been that it doesn’t help mitigate symptoms, I think it’s pretty clear it does that. But it’s also not nearly effective as what they thought it was going to be at keeping you from contracting/transmitting. They have some short term data (and one could say it’s relatively safe, but IMO they are sweeping lots of vaccine issues right under the rug), but when it comes to them saying it’s safe long term, it’s a total hypothesis….they have ZERO clue.
I guess my question is how would you know when they did have a clue? If they said good enough after 2 years, would that be satisfactory? How do we know nothing happens ten years later? Ultimately I don't personally know the answers, and the people I'd depend on to know are the same people currently saying these vaccines are worthwhile.
I would say from what I have read, MRNA (as clearly as it can be for someone at my knowledge level) doesn't seem like the kind of thing that is likely to lead to long term issues. This is pretty representative of what I've read:
https://medical.mit.edu/covid-19-update ... 19-vaccine
The Pfizer/Biotech and Moderna mRNA vaccines contain an mRNA molecule wrapped in a lipid nanoparticle (LNP) envelope. The LNP is a biodegradable ball of fat with a half-life of about two hours. It lasts just long enough to protect the mRNA from degrading before it enters your cells. The mRNA itself is a blueprint — detailed instructions for the cells to create harmless pieces of a specific spike protein that’s found on the surface of the SARS-CoV-2 virus. Once the mRNA uses the body’s cells to make this spike protein piece, the mRNA also degrades and disappears, as mRNA always does.
In mammalian cells, mRNA lifetimes range from several minutes to several days. The mRNA molecule in a COVID-19 vaccine begins to disintegrate after about six hours and is completely gone in 48. Meanwhile, your body recognizes that the spike protein doesn’t belong and starts creating antibodies to remove it. These are the same kind of antibodies you would make during a natural COVID-19 illness, and it prepares your immune system to fight the actual virus if you encounter it.
“After two days, there’s nothing left of the mRNA, and the lipid envelope is long gone,” Stuopis emphasizes. “Nothing sticks around to cause problems in the future. And while the mRNA inserts itself into the body’s cells and uses the cellular machinery to create that harmless piece of spike protein, it cannot possibly affect your DNA, because it never enters the cell’s nucleus, where your DNA resides.”
We're not talking about something like thalidomide, where a chemical was introduced that led to birth defects. We're just reprogramming cells to be prepared to fight the virus before we get it, just as they would if we actually caught it. The biggest risks appear to be short term reactions like infection. The article mentions some occurences of myocarditis, that appear to be treatable.
